CellMechBio: The Influence of Cellular Mechanobiology on Organ Development

Spatially structured models of viral dynamics: a scoping review

T Williams, JM McCaw, JM Osborne

2025-12-18

SUMMARYThere is growing recognition in both the experimental and modeling literature of the importance of spatial structure to the..

Quantifying biological heterogeneity in nano-engineered particle-cell interaction experiments

RJ Murphy, M Faria, JM Osborne, ST Johnston

2025-09-17

Nano-engineered particles are a promising tool for medical diagnostics, biomedical imaging and targeted drug delivery. Fundamental..

Accounting for the geometry of the respiratory tract in viral infections

T Williams, JM McCaw, JM Osborne

2025-06-01

Increasingly, experimentalists and modellers alike have come to recognise the important role of spatial structure in infection dyn..

Competing mechanisms for the buckling of an epithelial monolayer identified using multicellular simulation

PJ Brown, JEF Green, BJ Binder, JM Osborne

2025-02-01

A model using the rigid body multi-cellular framework (RBMCF) is implemented to investigate the mechanisms of buckling of an epith..

An adaptive numerical method for multi-cellular simulations of tissue development and maintenance

JM Osborne

2024-11-07

In recent years, multi-cellular models, where cells are represented as individual interacting entities, are becoming ever popular...

Spatial information allows inference of the prevalence of direct cell–to–cell viral infection

T Williams, JM McCaw, JM Osborne

2024-07-01

The role of direct cell–to–cell spread in viral infections—where virions spread between host and susceptible cells without needing..

Advancements in multicellular simulations

DPJ Germano, JM Osborne

2024-05-01

Multicellular modeling is increasingly being used to understand biological systems. SimuCell3D is a tool that allows mechanically ..